|“||It is through my threads that all life is born. You must not tamper with destiny, Kratos. You will destroy everything.||”|
God of War IIEdit
In God of War, she is depicted as a monstrously bloated humanoid silk worm-like creature with multiple arms and breasts. She is immobile (unlike her sisters), and resides deep within the Loom Chamber.
After battling Lahkesis and Atropos, Kratos finds Clotho, who warns him not to tamper with the threads of life. Kratos defies Clotho in order to complete his goal, taking her body out in various stages while she attempted to hold him off with her many arms. Ultimately, she met her demise when Kratos impaled her skull with a large, swinging, blade-like pendulum (which is found at the bottom of Clotho's apparatus).
- She is by far the largest of the Sisters of Fate, as well as the youngest. Ironically, Clotho is quite ugly compared to most depictions of her in mythology.
- Despite being – presumably – capable to control time, Clotho only attacks Kratos by hitting him with her arms; she isn't even able to create balls of energy, like her sisters. Also, ironically, Kratos can use time control against her, since he can activate the Amulet of the Fates to slow down time, thereby slowing Clotho's movements.